• Dr. Harsimranjeet Singh, ND

Intravenous Vitamin C to Reduce Fatigue and Improve Energy

Fatigue, especially chronic fatigue syndrome, is an increasingly common condition and symptom that is experienced in full-time workers. The burn-out from working demanding jobs and long hours is becoming more common at an alarmingly quick rate.

It is estimated that almost 28% of adults complain of fatigue. And almost 31% of adults that visit their family doctors complain of fatigue. There are many things that can be done to help reduce symptoms of fatigue and help improve worker productivity.

One of the main causes of fatigue in the body, from a biochemical perspective, is oxidative stress. Inflammatory cytokines in the body have a strong positive correlation with increasing symptoms of fatigue.

In a randomized clinical trial among 141 healthy office workers, half were given 10 grams of Vitamin C by Intravenous infusion and the other half were given just saline by IV as well.

When measuring outcomes in both groups, there was statistically significant reduction in self-reported feeling of fatigue in the group of office workers which received the Vitamin C IV Infusion compared to the ones who received just saline not reporting any reduction in fatigue.

It was also incredible to see that markers of oxidative stress were reduced significantly in the group that received the high dose antioxidant Vitamin C by IV. The researchers concluded that high dose Vitamin C for fatigue is both a safe and effective therapy.


1. Suh, S.-Y., Bae, W. K., Ahn, H.-Y., Choi, S.-E., Jung, G.-C., & Yeom, C. H. (2012). Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial. Nutrition Journal, 11(1).

This article is in no way a replacement for medical advice or medical care, it is advised that anyone concerned about their Health should speak with their Naturopathic Doctor.

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