Artificial Insemination (IUI)

Can vitamins be helpful for artificial insemination?


The use of nutrients and vitamins to help with fertility treatments is a quickly growing field of research. Many studies have evaluated for the benefits of important nutrients and how they may influence the treatment outcomes with assisted reproductive technologies (IVF, ICSI, and IUI).


The use of the supplement Coenzyme Q10 seems to support quality of eggs, reduce chromosomal issues in the eggs, and increase the success rate of assisted reproductive technologies [1].


Another important supplement is Vitamin D, which can improve success rates of assisted reproductive technologies by up to 6% [2, 3]. 


There are many other studies evaluating for the use of nutrients and vitamins in both men and women which have demonstrated significant improvements in fertility treatment outcomes: improving the pregnancy rate, improving the percentage of women that carry to term, and also reduce common uncomfortable symptoms during pregnancy. 


In addition to supporting your body and fertility with the use of nutraceuticals, it is important to maintain a healthy body-mass-index (BMI), being overweight and underweight may significantly reduce the chances of a positive outcome [4].


Eating a diet that has plentiful vegetables and fruits, reducing or stopping use of tobacco, marijuana, caffeine, and alcohol may also improve the chances of a successful pregnancy [5-7].



  1. Özcan, P., Fıçıcıoğlu, C., Kizilkale, O., Yesiladali, M., Tok, O. E., Ozkan, F., & Esrefoglu, M. (2016). Can Coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage? Journal of Assisted Reproduction and Genetics, 33(9), 1223–1230.

  2. Skowrońska, P., Pastuszek, E., Kuczyński, W., Jaszczoł, M., Kuć, P., Jakiel, G., Łukaszuk, K. (2016). The role of vitamin D in reproductive dysfunction in women – a systematic review. Annals of Agricultural and Environmental Medicine, 23(4), 671–676.

  3. Zhao, J., Huang, X., Xu, B., Yan, Y., Zhang, Q., & Li, Y. (2018). Whether vitamin D was associated with clinical outcome after IVF/ICSI: a systematic review and meta-analysis. Reproductive Biology and Endocrinology, 16(1).

  4. Purewal, S., Chapman, S. C. E., & O. B. A Van Den Akker. (2017). A systematic review and meta-analysis of lifestyle and body mass index predictors of successful assisted reproductive technologies. Journal of Psychosomatic Obstetrics & Gynecology, 40(1), 2–18.

  5. Dodge, L. E., Missmer, S. A., Thornton, K. L., & Hacker, M. R. (2017). Women’s alcohol consumption and cumulative incidence of live birth following in vitro fertilization. Journal of Assisted Reproduction and Genetics, 34(7), 877–883.

  6. Karmon, A. E., Toth, T. L., Chiu, Y.-H., Gaskins, A. J., Tanrikut, C., Wright, D. L., Chavarro, J. E. (2017). Male caffeine and alcohol intake in relation to semen parameters and in vitro fertilization outcomes among fertility patients. Andrology, 5(2), 354–361.

  7. Payne, K. S., Mazur, D. J., Hotaling, J. M., & Pastuszak, A. W. (2019). Cannabis and Male Fertility: A Systematic Review. Journal of Urology, 202(4), 674–681.